“More Than Any Other Single Factor, Nitric Oxide May Be The Key To Living A Longer, Healthier Life.”

LOUISE J. IGNARRO

The Research

Nobel Prize In Medicine Laureate

“I am convinced that Nitric Oxide can age-proof your cardiovascular system, keeping it much fitter than your chronological age would indicate. Repairing the damage wrought by cardiovascular disease without risky and often ineffective surgery had long been considered impossible. I was awarded the Nobel Prize in Medicine for making that thinking obsolete.

Now we know we can reverse cardiovascular impairment naturally—with the body’s internally manufactured ‘wonder drug’, Nitric Oxide.

Your body has four essential bodily processes: vascular tone, coagulation, inflammation and oxidation. Nitric Oxide therapy can make a lifesaving difference to your health by enhancing the positive and eradicating the negative in each of them.”

[Louise J. Ignarro]

In 1998, three scientists were jointly awarded a NOBEL PRIZE in MEDICINE for discovering L-arginine as a singling molecule for the production of Nitric Oxide in the body—effectively targeting the underlying cause of most Cardiovascular Disease.

Leading Scientists Agree

The world’s most published researcher on Nitric Oxide, world-wide, is German scientist, Dr Rainer Böger (pictured above), whose research discovered how to ‘turbo-charge’ the level and longevity of Nitric Oxide. His findings show that combining medicinal grade L-arginine and L-citrulline at a particular ratio extends the level and longevity of the Nitric Oxide from only a few minutes to over twelve hours.

This is important because instead of needing many doses per day to maintain an effective therapeutic level of Nitric Oxide in the blood (something you’ll not likely hear about from suppliers), with a sufficiently high quality product (there is none as high as Nitric Oxide Infusion) only two doses per day are required (one in the morning, one in the evening), so significant and sometimes dramatic results, as well as cost/savings, can be achieved.

Renowned Cardiologist & Endocrinologist, Dr Joe Pendergast

Dr Joe Pendergast was renowned for his significant results using Nitric Oxide and cardiovascular health over the last 30 years, long before the Nobel Prize shone the spotlight on the humble amino acid.

He was perhaps one of the world’s most recognised researchers and practitioners in Nitric Oxide and its role in reversing Cardiovascular Disease.

"I believe that Nitric Oxide is the single most important discovery in preventing heart disease that I have seen during the course of my medical career. Of course there are many treatments for heart disease, but I haven’t seen anything as effective.

We cannot ignore the power of Nitric Oxide anymore. Heart Disease is the number one killer for both men and women. The main factors are arteriosclerosis—hardening of the arteries, and atherosclerosis—buildup on the arterial lining. Nitric Oxide reverses both problems.”

Dr. John Cooke, Director Of Vascular Medicine At Stanford University, Author Of The Book, “The Cardiovascular Cure”

Let me “…introduce you to the magic inside your blood vessels. It comes in the shape of a molecule, one of the simplest molecules found in nature. This molecule is Nitric Oxide, or N.O., a substance so powerful that it can actually protect you from heart attack and stroke.

N.O. is your body’s own built-in, natural protection against heart disease.”

Research Papers

  1. Kochupurackal P, et al. Nitric oxide:an antioxidant and neuroprotector. Annals of the New York Academy of Sciences. 2002; 962:389-401.
  2. Kumar CA, Das UN. Lipid peroxides, antioxidants and nitric oxide in patients with pre-eclampsia and essential hypertension. Med Sci Monitor. 2000 Sep-Oct; 6(5):901-7.
  3. Brown, M.D., Dengel, D.R., Supiano, M.A. Nitric Oxide Biomarkers are Associated with the Blood Pressure-Lowering Effects of Dietary Sodium Restriction in Older Hypertensives. Circulation (Abstract I). 1997; 96:I-539.
  4. Rosano, G.M.C., Tanina, G., Cerquetani, E., Leonardo, F., Pelliccia, F., Bonfigli, B., and Chierchia, F.L. L-arginine Improves Endothelial Function in Newly Diagnosed Hypertensives. The Journal of the American College of Cardiology (Supplement A). 1998; 31:262a
  5. Moncada, F., Palmer, R.M.J., Higgs, E.A. The Discovery of Nitric Oxide as the Endogenous Nitrovasodilator. Hypertension. 1988; 12:365-72.
  6. Pautler EL. The possible role and treatment of deficient microcirculation regulation in age-associated memory impairment. Med Hypotheses. 1994 Jun; 42(6):363- 6.
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  8. Ghigo E, Arvat E, Gianotti L, et al. Hypothalamic growth hormone-insulin-like growth facto-1 axis across the human life span. J Pediatr Endocrinol Metab.2000; 13 Suppl 6:1493-502.
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  10. Korting GE, Smith SD, Wheeler MA, Weiss RM, Foster HE. A randomized double-blind study of oral L-arginine for treatment of interstitial cystitis. J Urol. 1999 Feb; 161(2):558-65.
  11. Piatti PM, Monti LD, Valsecchi G, et al. Long term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetes. Diabetes Care. 2001 May; 24(5):875-80.
  12. Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced diabetes mellitus. Free Radic Biol Med. 1998 Nov 1; 25(7):757-65.
  13. Heys SD, et al. Dietary supplementation with L-arginine: Modulation of tumor infiltrating lymphocytes in patients with colorectal cancer. Br J Surg. 1997 Feb; 84(2):238-41.
  14. Brittenden J, et al. Dietary supplementation with L-arginine in patients with breast cancer (> 4cm.) receiving multi-modality treatment: report of a feasibility study. Br J Cancer. 1994 May; 69(5):918-21.
  15. Khedara A, Kawai Y Kayashita J Kato N. Feeding rats the nitric oxide synthase inhibitor, L-N(omega) nitroarginine, elevates serum triglycerides and cholesterol and lowers hepatic fatty acid oxidation. J Nutr. 1996 Oct; 126(10):2563-7.
  16. Chen J, Wollman Y, Chernichovsky T, et al. Effect of high dose nitric oxide donor L-arginine in men with organic erectile dysfunction. BJU Int. 1999 Feb; 83(3):269-73.
  17. Wolf A, et al. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. J Am Coll Cardiol. 1997 Mar 1; 29(3):479.
  18. Podjarny, E., et al. Pregnancy-induced hypertension in rats with adriamycin nephropathy is associated with inadequate production of nitric oxide. Hypertension. 1997; 29:986-991.
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