“More Than Any Other Single Factor, Nitric Oxide May Be The Key To Living A Longer, Healthier Life.”

LOUISE J. IGNARRO

The Research

Nitric Oxide Research Recognition

In 1998, nitric oxide research was recognised with the Nobel Prize in Physiology or Medicine, highlighting its significance in human biology and advancing scientific understanding of how it is produced and functions within the body.

Nitric oxide is generated from amino acids such as L-arginine and plays an important role in supporting normal blood vessel function, circulation, and cellular signalling processes.

The recognition of nitric oxide research helped establish its importance in supporting vascular function, with ongoing research continuing to explore its role in overall health and wellbeing.

Designed for Consistent Nitric Oxide Support

Scientific research has explored how combining L-arginine and L-citrulline may help support the body’s natural nitric oxide pathways. These amino acids play complementary roles in nitric oxide production.

This formulation approach is designed to support nitric oxide levels over an extended period when used consistently as part of a daily routine.

Simple Daily Routine

To support consistency, Nitric Oxide Infusion® is designed to be taken twice daily, approximately 12 hours apart. This allows for convenient integration into your morning and evening routine.

Individual responses may vary, and results are best supported alongside a balanced diet and healthy lifestyle.

Scientific Interest in Nitric Oxide

Research into nitric oxide has increased significantly over recent decades, with growing scientific interest in its role in supporting normal blood flow and vascular function.

Nitric oxide is produced naturally in the body and plays a role in processes that support circulation and blood vessel function. Amino acids such as L-arginine are involved in supporting the body’s natural nitric oxide pathways.

Why It Matters

Supporting healthy circulation is an important part of overall wellbeing and may be maintained through a balanced diet, regular physical activity, and healthy lifestyle choices

As we age, the body’s natural production of nitric oxide may decline. Supporting these natural pathways can help maintain healthy circulation as part of a consistent daily routine.

Understanding Nitric Oxide

Nitric oxide is a naturally occurring molecule in the body and has been the subject of extensive scientific research. It plays a role in supporting normal blood flow and vascular function.

Produced within the blood vessels, nitric oxide is involved in processes that support circulation and overall vascular health. Amino acids such as L-arginine contribute to the body’s natural nitric oxide pathways.

Maintaining healthy circulation is an important part of overall wellbeing and can be supported through a balanced diet, regular physical activity, and healthy lifestyle choices.

Research Papers

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  3. Brown, M.D., Dengel, D.R., Supiano, M.A. Nitric Oxide Biomarkers are Associated with the Blood Pressure-Lowering Effects of Dietary Sodium Restriction in Older Hypertensives. Circulation (Abstract I). 1997; 96:I-539.
  4. Rosano, G.M.C., Tanina, G., Cerquetani, E., Leonardo, F., Pelliccia, F., Bonfigli, B., and Chierchia, F.L. L-arginine Improves Endothelial Function in Newly Diagnosed Hypertensives. The Journal of the American College of Cardiology (Supplement A). 1998; 31:262a
  5. Moncada, F., Palmer, R.M.J., Higgs, E.A. The Discovery of Nitric Oxide as the Endogenous Nitrovasodilator. Hypertension. 1988; 12:365-72.
  6. Pautler EL. The possible role and treatment of deficient microcirculation regulation in age-associated memory impairment. Med Hypotheses. 1994 Jun; 42(6):363- 6.
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  8. Ghigo E, Arvat E, Gianotti L, et al. Hypothalamic growth hormone-insulin-like growth facto-1 axis across the human life span. J Pediatr Endocrinol Metab.2000; 13 Suppl 6:1493-502.
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  11. Piatti PM, Monti LD, Valsecchi G, et al. Long term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetes. Diabetes Care. 2001 May; 24(5):875-80.
  12. Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced diabetes mellitus. Free Radic Biol Med. 1998 Nov 1; 25(7):757-65.
  13. Heys SD, et al. Dietary supplementation with L-arginine: Modulation of tumor infiltrating lymphocytes in patients with colorectal cancer. Br J Surg. 1997 Feb; 84(2):238-41.
  14. Brittenden J, et al. Dietary supplementation with L-arginine in patients with breast cancer (> 4cm.) receiving multi-modality treatment: report of a feasibility study. Br J Cancer. 1994 May; 69(5):918-21.
  15. Khedara A, Kawai Y Kayashita J Kato N. Feeding rats the nitric oxide synthase inhibitor, L-N(omega) nitroarginine, elevates serum triglycerides and cholesterol and lowers hepatic fatty acid oxidation. J Nutr. 1996 Oct; 126(10):2563-7.
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  17. Wolf A, et al. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. J Am Coll Cardiol. 1997 Mar 1; 29(3):479.
  18. Podjarny, E., et al. Pregnancy-induced hypertension in rats with adriamycin nephropathy is associated with inadequate production of nitric oxide. Hypertension. 1997; 29:986-991.
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